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The #1 Disease-Fighting Snack (Nuts)
Antioxidant-rich Fruits
BBQ meat concerns and health tips
Citral
12 Most Contaminated Fruits & Vegetables (For updates, check-out
EWG.org)
Garlic flunks major test.
A double-blind clinical trial of garlic and garlic supplements found no improvement in
cholesterol levels among 192 adults with moderately elevated (130 to 190mg/dL)
LDL-cholesterol levels. The participants were randomly divided into groups that
received raw garlic, a powdered garlic supplement, an aged garlic extract supplement,
or a placebo for six months. Garlic product doses equivalent to an average-sized garlic
clove were consumed 6 days per week for 6 months. The study found no statistically
significant difference in high-density lipoprotein cholesterol, triglyceride levels, or total
cholesterol-high-density lipoprotein cholesterol ratio in the four groups. [Gardner CD
and others. The researchers noted that idea that garlic could improve cholesterol levels
was considered plausible because about 85% of more than 110 animal studies found
positive effects and human clinical trials conducted before 1995 with garlic powder
tablets suggested a modest beneficial effect. However: (a) animal studies may not be
applicable to humans, (b) the pre-1995 human trials were not well-designed, and (c)
six more recent trials found no benefit. The researchers concluded:
Based on our results and those of other recent trials, physicians can advise patients
with moderately elevated LDL . . . concentrations that garlic supplements or dietary
garlic in reasonable doses are unlikely to produce lipid benefits. While garlic may have
other health effects, such as increased fibrinolysis, decreased atherosclerosis, or
anticarcinogenic properties, we would argue that these possible effects also should be
scrutinized in large, carefully designed trials with chemically defined garlic products.
[Gardner CD.
Effect of raw garlic vs commercial garlic supplements on plasma lipid concentrations in
adults with moderate hypercholesterolemia. Archives of Internal Medicine
167:346-353, 2007]
http://archinte.ama-assn.org/cgi/content/full/167/4/346
Because several drugs have been proven to improve cholesterol levels and reduce the
incidence of heart attacks and death, it also can be argued that substituting garlic for
that purpose is senseless. In a Los Angeles Times interview, lead author Christopher
Gardner said:
"It just doesn't work. If garlic was going to work, in one form or other, then it would
have worked in our study. The lack of effect was compelling and clear." The study was
supported by a $1.5 million NIH grant.
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